Tim4 gene name
Web20 giu 2012 · Establishment of Tim4-deficient mice.(A) Targeting of the Tim4 gene. Schematic representation of the wild-type and mutant loci of the Tim4 gene and the targeting vector. Exons are represented by closed boxes. The targeting vector carries the neomycin resistance gene (neo) and the gene encoding the Diphtheria toxin A fragment … Web21 feb 2006 · Status. UniProtKB unreviewed (TrEMBL) Organism. Homo sapiens (Human) Amino acids. 262. Protein existence. Evidence at transcript level. Annotation score.
Tim4 gene name
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Web26 set 2024 · Gene silencing. The TIM4 gene in splenic DCs and the TIM1 gene in CD4 T cells were knocked down by RNA interfer-ence with reagent kits [Lipofectamine™ 3000 Transfection Reagent (L3000015); Invitrogen, Shanghai, China] following the manufacturer's instructions. The effect of gene silenc ing was assessed by western blotting. Flow … WebT-cell immunoglobulin and mucin domain-containing protein 4 (UniProt Q6U7R4; also known as SMUCKLER, Spleen, mucin-containing, knockout of lymphotoxin protein, T-cell immunoglobulin mucin receptor 4, T-cell membrane protein 4, TIM-4, TIMD-4) is encoded by the Timd4 (also known as Tim4) gene (Gene ID 276891) in murine species.
WebTIM-4 (TIMD4) Antibodies TIM-4 (TIMD4) Antibodies Antibodies that detect TIM-4 (TIMD4) can be used in several scientific applications, including Immunohistochemistry, Western … Web12 lug 2024 · Cavity-resident macrophages express high levels of Tim-4, a receptor for phosphatidylserine (PS), and this is associated with reduced numbers of CD8+T cells with tumor-reactive features in pleural effusions and peritoneal ascites from patients with cancer.
WebBelongs to the immunoglobulin superfamily. TIM family. Tim4/TIMD4 protein name Recommended name T-cell immunoglobulin and mucin domain-containing protein 4 … WebAlias : TIMD4, TIM4, SMUCKLER T-cell immunoglobulin and mucin domain containing 4. T-cell immunoglobulin mucin receptor 4. T-cell membrane protein 4. Back to the top Specifications Human TIM4 isoform 1 (pUNO1-hTIM4a) Genbank : JX049980.1 ORF size : 1137 bp Subclone : BspLU11I - NheI Back to the top pUNO1 Contents 20 µg of …
Web28 mar 2024 · Summary. Official Symbol. TIMD4 provided by HGNC. Official Full Name. T cell immunoglobulin and mucin domain containing 4 provided by HGNC. Primary …
WebTIM-4 is also known as Spleen, mucin-containing, knockout of lymphotoxin protein (SMUCKLER). TIM-4 is a single-pass type I membrane transmembrane glycoprotein … spring boot filterconfigWebThe Tissue section contains information regarding the expression profile of human gene both on the mRNA and protein level. The protein expression data from 44 normal tissue … spring boot filter read request bodyWebTIM-4 (T cell; immunoglobulin; mucin-4), also known as SMUCKLER, is a 60 kDa member of the TIM family of immune regulating proteins. TIMs are type I transmembrane proteins … spring boot filter authWebBackground: Dendritic cell (DC)-derived immunoglobulin domain molecule (TIM)4 plays a critical role in the initiation of T helper (Th)2 polarization. Vitamin D (VitD) involves the regulation of a number of immune responses. Objectives: This study tests a hypothesis that VitD regulates TIM4 expression in DCs. Methods: Peripheral blood samples were … shepherds gutteringWebTIM-4 (T cell; immunoglobulin; mucin-4), also known as SMUCKLER, is a 60 kDa member of the TIM family of immune regulating proteins. TIMs are type I transmembrane proteins … springboot + flowableWebTargeted disruption of the Tim4 gene The Tim4-targeted mice were generated as custom order by Unitech (Kashiwa, Chiba, Japan). In brief, the Tim4 chromosomal gene was isolated from BAC clones of C57BL/6 mice, and its exon 1 and most of exon 2 were replaced by a coding sequence for Venus and neo gene (Fig. 1). springboot flowable 教程WebT cell immunoglobulin and mucin domains containing protein 4 (TIM4, TIMD4) is a phosphatidylserine receptor that mediates phagocytosis of apoptotic cells. It is involved in the regulation of T helper cells (Th1 and Th2) immune responses. TIM4 binds apoptotic cells by recognizing phosphatidylserine through its immunoglobulin domain. shepherds gutter