網頁The spectacularly beautiful images to the left (all courtesy of J. Lichtman) are the happy result of the search to visualize the brain’s circuits at work in a living animal. The Brainbow was a revelation that enabled scientists for the first time to study neurons in live tissue. The method was first developed by Harvard’s Joshua Sanes and ... 網頁2011年7月8日 · We constructed a CRE/lox clonal deletion system named BOB (Brother of Brainbow), which allows tissue-specific elimination of gametophytic essential genes from …
工具鼠的工具鼠,Reporter 鼠简介 - 知乎
網頁2007年12月1日 · The ability of the Brainbow system to label uniquely many individual cells within a population may facilitate the analysis of neuronal circuitry on a large scale. Brainbow-1: stochastic ... 網頁Brainbow鼠利用了3种不同的lox序列:lox2272、loxN和loxp。当遇到不同的Cre鼠切割的序列不同,能够发出的荧光也就不同。打靶方式如图6 。 图6. Brainbow鼠的打靶策略[4] 是不是看着有点晕?其实道理还是很简单的啦,每一段带有发光集团的序列里还有一小 ... feldman new hudson hyundai
Distinct Cell-Autonomous Functions of …
網頁cell-autonomous functions of RETINOBLASTOMA-RELATED in Arabidopsis stem cells revealed by the brother of Brainbow clonal analysis system. Plant Cell 23(7):2581–2591 … 網頁To circumvent this obstacle, we designed a clonal deletion system named BOB (Brother of Brainbow) in which null mutant sectors marked by double fluorescence are generated in a fully complemented wild-type background. In this system, both copies of a ... 網頁To examine these challenging genes, Wachsman et al. (pages 2581–2591) developed a system called Brother of Brainbow (BOB). In the BOB system, plants are homozygous … feldman new hudson staff