WebKIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice. Betaine ameliorates schizophrenic traits by functionally … WebCollapsin response mediator protein 2 (CRMP2) has long been identified as a microtubule-binding protein that regulates neuronal polarity in vitro. Recent studies provide new insights into the roles of CRMP2 in neuronal migration and subsequent neuronal differentiation.
Betaine ameliorates schizophrenic traits by functionally …
WebBackground. Collapsin Response Mediator Protein-2 (CRMP-2) is expressed at high levels in the developing nervous system and plays a critical role in axonal outgrowth by specifying axon/dendrite fate and establishing neuronal polarity (1,2). CRMP-2 enhances axon elongation and branching by binding to tubulin heterodimers to promote microtubule ... Web19 jan. 2024 · Breast cancer is the most common malignant tumors in women. Kinesin family member 3B (KIF3B) is a critical regulator in mitotic progression. The objective of this study was to explore the expression, regulation, and mechanism of KIF3B in 103 cases of breast cancer tissues, 35 metastatic lymph nodes and breast cancer cell lines, including … cabins near big south fork national park
CRMPs Function in Neurons and Glial Cells: Potential Therapeutic ...
Web11 apr. 2024 · Background and PurposeAn increasing number of autoimmune encephalitis (AE)-associated autoantibodies have been successfully characterized. However, many cases of AE remain unexplained on account of unknown antibodies. The aim of the present study was to identify a novel antibody against collapsin response mediator protein 2 … WebAccording to a deficiency in the transport of collapsin response mediator protein 2 (CRMP2) by the KIF3 motor, we identified a significant reduction in lamellipodial … Web10 aug. 2024 · CRMP2 interacts with RECK to prevent its degradation and blocks NF-κB and Wnt signaling To determine the downstream pathways influenced by CRMP2, we performed RNA sequencing (RNA-seq) analysis. cabins near billings mt