Clathrin heavy chain翻译
WebClathrin triskelions, composed of 3 heavy chains and 3 light chains, are the basic subunits of the clathrin coat. In the presence of light chains, hub assembly is influenced by both the pH and the concentration of calcium. Interacts with HIP1. Interacts with DENND1A, DENND1B and DENND1C. Interacts with OCRL. Interacts with ERBB2. WebClathrin heavy chain; subunit of the major coat protein involved in intracellular protein transport and endocytosis; the clathrin triskelion is a trimeric molecule composed of three heavy chains that radiate from a vertex and three light chains which bind noncovalently near the vertex of the triskelion; ...
Clathrin heavy chain翻译
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WebApr 12, 2024 · The clathrin’s three-legged structure is formed by extending these heavy chains. The clathrin N-terminal domain, which is folded into a seven-bladed-propeller, is located near the distal end of the legs, while the C terminus is located near the apex [32,35]. Clathrin-mediated endocytosis regulates the amounts of key plasma membrane proteins ... WebClathrin heavy chain (Chc) is a constituent of clathrin-coated vesicles and serves important functions in endocytosis and intracellular membrane trafficking but appears to …
WebClathrin. (A) Organization of the heavy- and light-chain polypeptide chains. The name or phase designating various segments appears above the corresponding region of the … http://www.jinpanmed.cn/archives/date/2024/03/29/page/8
WebOct 20, 2014 · Abstract. Clathrin heavy chain has been shown to be important for viability, embryogenesis, and RNA interference (RNAi) in arthropods such as Drosophila … Webclathrin heavy chain binding Source:GO_Central. 1 publication. Molecular Function: identical protein binding Source:IntAct. 1 publication. ... Clathrin coats are formed from molecules containing 3 heavy chains and 3 light chains (By similarity). Interacts with TPLATE and CHC2 By similarity. 1 publication. Binary interactions. Type. Entry 1 ...
WebApr 22, 2024 · Upon treatment with endosidin9-17, the clathrin heavy chain fails to be assembled into coat structures, leading to reduced endosome formation and inhibited cargo protein endocytosis, which affects ...
WebAug 1, 1993 · The clathrin heavy chain (HC) is the major structural polypeptide of the cytoplasmic surface lattice of clathrin-coated pits and vesicles. As a genetic approach to understanding the role of clathrin in cellular morphogenesis and developmental signal transduction, a clathrin heavy chain (Chc) gene of Drosophila melanogaster has been … huer\\u0027s psychology of intelligence analysisWebClathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the … huertly house interiorWebApr 9, 2024 · Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy … huerty petrochemicalWebWe demonstrate a specific interaction with clathrin heavy chain, alpha- and beta-tubulin, and actin. These interactions were dependent upon myristoylation of neurocalcin delta indicating that the N-terminal myristoyl group may be important for protein-protein interactions in addition to membrane association. Direct binding of neurocalcin delta ... huerto aestheticWebJan 13, 2012 · The reciprocal binding site on clathrin is the globular ‘terminal domain’ (TD) at the N-terminus of the clathrin heavy chain (HC) 18. Structurally, the TD is folded into a seven-bladed β-propeller 19 and this represents the region of the outer triskelion positioned closest to the membrane surface in the assembled coat 20 (Figure 1). hue salon windsor caWebAntibodies that detect Clathrin Heavy Chain can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation and ELISA. These antibodies target Clathrin Heavy Chain in Human, Mouse, Rat, Bovine and Porcine samples. Our Clathrin Heavy Chain polyclonal, monoclonal and ... huerty petrochemical houstonWebMar 29, 2024 · Summary. Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized … huertocity