WebFeb 28, 2024 · Breast cancer has grown to be the second leading cause of cancer-related deaths in women. Only a few treatment options are available for breast cancer due to the widespread occurrence of chemoresistance, which emphasizes the need to discover and develop new methods to treat this disease. Signal transducer and activator of … WebApr 13, 2024 · Published Apr 13, 2024. + Follow. Cancer is a broad term for a variety of disorders characterised by the uncontrollable division of aberrant cells with the ability to infiltrate and destroy normal ...
Molecular docking and molecular dynamic studies: …
WebJun 15, 2024 · Breast cancer is one of the most common cancers found in women. It is the second leading cause of cancer-related death after lung cancer. ... Prolinedithiocarbamate complex's binding to DNA was studied using an in vitro molecular docking anti-cancer activity assay. Molecular docking results showed the interaction of … WebKeeping this in view the present study was initiated to analyse interaction of tumour suppressor protein p53 (TP53) and breast cancer associated protein (BRCA1) as promising target against breast cancer. Using computational approaches such as protein-protein docking, hot spot analyses, molecular docking and molecular dynamics simulation … discopathy means
A High Dose of Calcitriol Inhibits Glycolysis and M2 ... - PubMed
WebJun 1, 2014 · Estrogen receptor alpha (ERα) plays a key role in the malignancy of breast cancer. Therefore, inhibitors for ERα can act as useful agents for the treatment of breast cancer. In the present study, we describe docking, toxicity prediction as a rational strategy for identification of novel hits or leads. Pubmed search showed, 76 6-methyl-1,3,8 … WebABSTRACT Comparative docking studies have been performed on 10 drug molecules, … WebApr 27, 2024 · The human hormone estrogen plays a vital role in breast cancer growth and cell development (Labrie et al. 1999).Estrogen receptors (ERs) are the specific hormone receptor of estrogen found to be express more in two-thirds of tumor cells compared to normal breast cells (Robinson et al. 2000).Among types of breast cancer, the estrogen … fourche transpalette