WebThis intriguing property of ASAH1 can be used by cancer cells to their advantage, by increasing the expression of the tumor promoter, sphingosine inside cells, thus creating a favorable environment for cancer growth. The different possibilities through which this enzyme serves its role in formation, progression and resistance of different types ... WebAssigned HPA protein class (es) for the encoded protein (s). Number of protein-coding transcripts from the gene as defined by Ensembl. A summary of the overall protein …
ASAH1 -Related Disorders - PubMed
WebThis publication includes mutations in ASAH1 collected through the Observational and Cross-Sectional Cohort Study of the Natural History and Phenotypic Spectrum of Farber … Webencoded by the ASAH1 gene. The possibility of broad-ened substrate specificity of AC during lysosomal lipid accumulation was investigated and experimental evi-dence for this is here presented. The remarkable ability of AC to initiate alternative metabolism of GSLs when regular catabolism fails is discussed in relation to its top hat plans are unfunded plans
Acid Ceramidase: A Novel Therapeutic Target in Cancer
WebASAH1 INFORMATION. Proteini. Full gene name according to HGNC. N-acylsphingosine amidohydrolase 1. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. ASAH1 (AC, ACDase, ASAH, FLJ21558, PHP32) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). Web29 mar 2024 · ASAH1 -related disorders comprise a spectrum that ranges from Farber disease (FD) to spinal muscular atrophy (SMA) with or without epilepsy. ASAH1 -related … Web2 gen 2024 · ASAH1 expression differed between histological ovarian cancer histotypes with most frequent expression in endometrioid and clear cell ovarian cancer, which are both associated with good prognosis. Stratified subgroup analyses within these histotypes did not reveal significant survival differences, but the power of the analysis may be limited by … top hat pizza menu new castle indiana